A balanced diet is important for people with myelofibrosis as proper nutrition can help support energy levels, immune function, and more.

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Myelofibrosis Meaning, Relationship between nutrition and myelofibrosis, Relationship between nutrition and myelofibrosis, The best food for myelofibrosis Patients, MPN Research Foundation Food Recommendation, Diet and health tips for people with myelofibrosis

Myelofibrosis Meaning: Myelofibrosis Treatment And Diet

It is a rare blood cancer that’s part of a group of disorders known as myeloproliferative neoplasms (MPN). People with MPNs have bone marrow stem cells that grow and reproduce abnormally, leading to extreme fatigue, fever, and bone pain.

There’s no specific myelofibrosis diet. But eating a balanced diet rich in fruits, vegetables, whole grains, protein sources, and healthy fats may help lower inflammation.

Relationship between nutrition and myelofibrosis

Cytokines are proteins released by cells that play a role in cell signalling. Some promote inflammation. Studies show inflammatory cytokines are abnormally high in people with myelofibrosis. Inflammation has been shown to affect the symptoms, progression, and outlook of MPNs like myelofibrosis.

Eating a well-balanced diet rich in nutritious foods and high in antioxidant and anti-inflammatory compounds may help reduce inflammation and improve other aspects of health.

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The best food for myelofibrosis Patients

According to some findings, the effect of diet on MPN symptoms and health outcomes is limited at this time.

Many doctors recommend healthy dietary patterns, such as imitating highly processed foods and eating smaller meals more frequently.

Some professionals also recommend people with myelofibrosis focus on consuming nutrient-dense foods rich in anti-inflammatory compounds like fruits and vegetables.

Also, experts recommend that people with myelofibrosis focus on consuming foods rich in specific nutrients that support the health of the blood and the immune system, including:

  • iron
  • vitamin B12
  • vitamin A
  • vitamin C
  • vitamin D
  • vitamin E
  • folate
  • copper

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MPN Research Foundation Food Recommendation

The MPN Research Foundation recommends including the following foods that are high in nutrients important for people with MPNs:

  • fruits and berries
  • green leafy vegetables
  • turmeric
  • nuts
  • whole grains
  • oily fish
  • green tea

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Food to limit when you have myelofibrosis

Experts recommend that people with MPNs reduce their consumption of ultra-processed foods that may contribute to inflammation and other health concerns.

In general, a nutritious diet limits the following foods:

  • fast food
  • sugary foods and beverages
  • ultra-processed snack foods
  • heavy amounts of alcohol

People with myelofibrosis can work with their healthcare team to develop a meal plan that supports healthy body weight maintenance and energy levels that meet their specific health needs.

Myelofibrosis treatments may also weaken your immune system and increase your risk of infection. Try to avoid eating:

  • raw meat, fish, or eggs
  • unpasteurized dairy
  • unwashed fruits and vegetables

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Diet and health tips for people with myelofibrosis

A person with myelofibrosis should work with their healthcare team, including a registered dietitian, to decide the best diet for their health needs.

Good nutrition and eating habits can help you maintain a moderate weight. A  recent study found being either underweight or overweight may increase or worsen symptoms for those with myelofibrosis.

Some Researchers are working on a trial to know whether the Mediterranean diet may benefit people with MPNs, including myelofibrosis. Researchers with the NUTRIENT Trial hope this diet pattern will reduce inflammation to improve MPN symptoms.

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Write and edit by Oluwaferanmi DJIMA On 09/12/23
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The takeaway: Myelofibrosis Treatment And Diet

Talk with your doctor about the best diet for you. Experts suggest the best diet for myelofibrosis is a well-rounded diet that provides optimal nutrition to support health.

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